The history of the development of therapeutic blockade - Pain Clinic

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The history of the development of therapeutic blockade


Development of local anesthesia and blockades preceds the invention in year 1850-1853. Syringe (C.C. Pravaz, France) and a hollow needle (F.A.Wood, Scotland) inorder to inject the drug into the damaged nerve.

In 1879, Vassily Konstantinovich Anrep in animal experiments revealed local anesthetic effect of cocaine.


K. Koller in 1884 for the first time under local anesthesia made surgery on the eye. In the same year W.S. Halstead (USA) implemented a nerve blockade with cocaine solution.


In 1886, A. L. Lukashevich developed an original method of anesthetising the fingers, which was the basis of conduction anesthesia.


In 1891, Mr. Otte - used a cancellous anesthesia in dentistry.


In 1904, Einhorn synthesized procaine, leading to a rapid development not only a local anesthetic, but also therapeutic blockade.


In 1906, H. Sellheim first used paravertebral blockade.


Vishnevskiy - has developed a method of creeping infiltration, cervical vagosympathetic , lumbar, perirenal, peresacral blockade.  A.V. Vishnevskiy has developed a position on the anti-inflammatory effects and reflex novocaine blockade at all levels of the nervous system, thereby justified the pathogenetic mechanisms in the method of  therapeutic blockade.


In 1947 - for the first time applied intraosseous anesthesia in surgery.


In 1953 - for the first time applied intraosseous therapeutic blockade.


The method of therapeutic blockade is the youngest, compared with other methods like - medication, surgery, psychotherapy, and numerous physiotherapies such as massage, acupuncture, mannual therapy, stretching, etc.


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